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| Data Details |
| Disease Name |
liver cirrhosis |
| Tissue |
liver |
| Database |
GEO |
| Data ID |
GSE98618 |
| Data Type |
sequence |
| Platform |
GPL18900 |
| Species |
homo sapiens |
| Sample Number |
56 |
| PubMed ID |
28843658 |
| Title |
Trunk events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma [multinodular CNV] |
| Data Description |
"Paraffin-embedded and fresh-frozen samples representing early steps of hepatocarcinogenesis were collected and gDNA was extracted. This cohort comprised: 29 dysplastic nodules (DN) -including low-grade and high-grade dysplasia (LGDN and HGDN)-; and 17 small tumors (sHCCs) -including 6 very-early and 11 early HCCs (veHCC and eHCC). When available matched cirrhotic tissues was also collected and extracted. Comparative Genomic Hybridization analysis was done using HumanOmniExpress-24 v1.1 BeadChip (Illumina) according to manufacturer's protocols. Previous treatment with the Infinium FFPE restoration kit (Illumina) was performed for FFPE samples. Log R ratio (LRR, reflecting total copy number) and B-allele frequency (BAF) obtained from GenomeStudio were used for CNV detection." |
| Keyword |
cirrhosis gDNA |
| Download |
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